Neurosyphilis

Infections of the central nervous system caused by TREPONEMA PALLIDUM which present with a variety of clinical syndromes. The initial phase of infection usually causes a mild or asymptomatic meningeal reaction. The meningovascular form may present acutely as BRAIN INFARCTION. The infection may also remain subclinical for several years. Late syndromes include general paresis; TABES DORSALIS; meningeal syphilis; syphilitic OPTIC ATROPHY; and spinal syphilis. General paresis is characterized by progressive DEMENTIA; DYSARTHRIA; TREMOR; MYOCLONUS; SEIZURES; and Argyll-Robertson pupils. (Adams et al., Principles of Neurology, 6th ed, pp722-8)

Also Known As:

General Paresis of the Insane; Central Nervous System Syphilis; General Paralysis; General Paralysis of the Insane; Neurosyphilis, Asymptomatic; Neurosyphilis, Gummatous; Neurosyphilis, Juvenile; Neurosyphilis, Secondary; Neurosyphilis, Symptomatic; Paralysis, General; Secondary Neurosyphilis; Syphilis, CNS; General Paresis; Juvenile Paresis; Paretic Neurosyphilis; Syphilis, Central Nervous System

Infections: 539155
- Central Nervous System Infections: 1428
  - Central Nervous System Bacterial Infections: 4
    - Neurosyphilis: 948
- Bacterial Infections and Mycoses: 1
  - Bacterial Infections: 25267
    - Gram-Negative Bacterial Infections: 959
      - Treponemal Infections: 53
        Syphilis: 7490
        Neurosyphilis: 948
      - Spirochaetales Infections: 28
        Treponemal Infections: 53
        Syphilis: 7490
        Neurosyphilis: 948
    - Central Nervous System Bacterial Infections: 4
      - Neurosyphilis: 948
Nervous System Diseases: 14737
- Central Nervous System Diseases: 4371
  - Central Nervous System Infections: 1428
    - Central Nervous System Bacterial Infections: 4
      - Neurosyphilis: 948

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A S Mushin Research Topics

Disease

Drug/Important Bio-Agent (IBA)